Heart Failure

Heart failure is a progressive and potentially fatal condition that is affecting over 60 million people worldwide and expected to increase as the population ages. Heart failure refers to the inability of the heart to pump sufficient blood through the body. Patients with chronic heart failure can present with either reduced (HFrEF) or preserved ejection fraction (HFpEF). HFrEF happens when the heart muscle does not contract effectively, and less blood is pumped out to the body often related to previous cardiac events, coronary artery disease and structural damage to the heart. HFpEF occurs when the heart muscle contracts normally but the left ventricle does not fill with enough blood, often due to stiffening of the heart muscle. Both, HFrEF and HFpEF, are related to co-morbidities like hypertension, coronary artery disease, obesity and type-2-diabetes. Heart failure is the leading cause of hospitalization in the US and Europe, and the number of patients across Asia is also increasing. The risk of death in people with heart failure rises with each hospital admission.

Latest Articles on Heart Failure

Organs Talk. The Podcast.

Have a listen to our third and final episode in season two of ‘Organs Talk: The Podcast’.

[Read more](/content/in/human-health/metabolic-diseases/its-your-heart-protect-it-podcast "Teaser headline Organs Talk. The Podcast."/index.html)

Heartbeat Moments – Winfried’s Story

Listen to Winfried’s Story on the impact heart failure can have in everyday life and the importance of heart health.

[Read more](/content/in/human-health/heart-diseases/heart-failure/winfrieds-story "Winfrieds Story"/index.html)

Understanding heart failure

Learn more about heart failure including its burden, symptoms, different types and association to other conditions.

[Read more](/content/in/human-health/heart-diseases/heart-failure/understanding-heart-failure "Understanding heart failure"/index.html)

Heartbeat Moments – Hyvelle’s Story

Listen to Hyvelle’s Story on the impact heart failure can have in everyday life and the importance of heart health.

[Read more](/content/in/human-health/heart-diseases/heart-failure/hyvelles-story "Hyvelles Story"/index.html)

US FDA approves Jardiance®

US FDA approves Jardiance® (empagliflozin) to treat adults living with heart failure with reduced ejection fraction.

[Read more](/content/in/disclaimer/bi?path=https%3A%2F%2Fwww.boehringer-ingelheim.us%2Fpress-release%2Fus-fda-approves-jardiance-empagliflozin-treat-adults-living-heart-failure-reduced "US FDA approves Jardiance®"/index.html)

EMPRISE real- world study design

Learn more about the design of the EMPRISE real-world evidence study.

[Read more](/content/in/pdf/200612empriseinfographic0 "EMPRISE real- world study design"/index.html)

Empagliflozin and hospitalization for heart failure pdf

Learn more about the results presented through the European Society of Cardiology’s HFA Discoveries program.

[Read more](/content/in/pdf/emprise-hfa-discoveries "Empagliflozin and hospitalization for heart failure pdf"/index.html)