Liver disease

The liver is a large and powerful organ that performs hundreds of essential functions. The most common causes of liver disease are viral infections, toxic poisoning and metabolic conditions such as obesity and type 2 diabetes. Metabolic dysfunction-associated steatotic liver disease (MASLD) or fatty liver disease, is the most common chronic liver disease. It can progress to metabolic dysfunction-associated steatohepatitis (MASH), where a long-term build-up of fat in the liver leads to inflammation and liver damage, which affects more than 250 million people worldwide.

Liver disease therapy areas

Metabolic dysfunction-associated steatohepatitis (MASH)

A dive into MASH, a progressive liver disease that affects millions of people worldwide.

Other cardiovascular, renal and metabolic diseases

Cardiovascular disease

Learn how cardiovascular disease is connected to other CRM conditions such as obesity, chronic kidney disease and type 2 diabetes.

Kidney disease

Find out why it is crucial to test people at risk of chronic kidney disease and how preserving the kidneys protects the heart.

Metabolic diseases

Did you know that type 2 diabetes and obesity affect the metabolic system, and in turn, can impact other organs in the body?

Discover how and why having one CRM condition increases the risk of developing others.

References

The liver and its vital connection to our overall health

How the liver is part of our interconnected cardiovascular, renal and metabolic system and why we need to look after it.